Ralf Hofheinz Selected Research

Combination Drug Therapy (Combination Chemotherapy)

7/2012	Pan-histone deacetylase inhibitor panobinostat sensitizes gastric cancer cells to anthracyclines via induction of CITED2.
12/2010	Induction chemotherapy before chemoradiotherapy and surgery for locally advanced rectal cancer : is it time for a randomized phase III trial?

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Ralf Hofheinz Research Topics

Disease

17	Neoplasms (Cancer) 01/2020 - 01/2009
11	Colorectal Neoplasms (Colorectal Cancer) 07/2019 - 11/2002
6	Adenocarcinoma 12/2019 - 03/2008
5	Rectal Neoplasms (Rectal Cancer) 01/2022 - 01/2010
3	Neoplasm Metastasis (Metastasis) 05/2013 - 01/2004
3	Stomach Neoplasms (Stomach Cancer) 12/2012 - 03/2008
2	Breast Neoplasms (Breast Cancer) 06/2023 - 01/2009
2	Fatigue 01/2020 - 03/2008
2	Glioblastoma (Glioblastoma Multiforme) 01/2020 - 01/2007
1	Squamous Cell Neoplasms (Squamous Cell Cancer) 01/2022
1	Disease Progression 01/2022
1	Bronchiolitis Obliterans 01/2022
1	Esophageal Squamous Cell Carcinoma 01/2022
1	Leukopenia 01/2020
1	Mucositis 01/2020
1	Neutropenia 01/2020
1	Sarcoma (Soft Tissue Sarcoma) 01/2020
1	Carcinoma (Carcinomatosis) 10/2016
1	Pathologic Complete Response 07/2012
1	Microsatellite Instability 01/2012
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 08/2010
1	Systemic Mastocytosis 08/2010
1	Hepatocellular Carcinoma (Hepatoma) 08/2010
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2009
1	Alopecia (Baldness) 03/2008
1	Anemia 03/2008
1	Vomiting 03/2008
1	Nausea 03/2008

Drug/Important Bio-Agent (IBA)

8	Fluorouracil (Carac)FDA LinkGeneric 08/2016 - 11/2002
5	Peptides (Polypeptides)IBA 01/2019 - 02/2010
4	Biomarkers (Surrogate Marker)IBA 12/2019 - 06/2012
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 07/2014 - 03/2008
4	Leucovorin (Folinic Acid)FDA Link 07/2014 - 11/2002
3	Imatinib Mesylate (Gleevec)FDA Link 01/2020 - 08/2010
3	Capecitabine (Xeloda)FDA Link 08/2016 - 01/2009
3	Cisplatin (Platino)FDA LinkGeneric 07/2014 - 03/2008
3	Peptide Hydrolases (Proteases)FDA Link 06/2014 - 07/2011
3	Irinotecan (Camptosar)FDA LinkGeneric 01/2012 - 11/2002
2	Trastuzumab (Herceptin)FDA Link 06/2023 - 01/2009
2	Monoclonal AntibodiesIBA 06/2023 - 09/2012
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2019 - 07/2012
2	Bevacizumab (Avastin)FDA Link 07/2019 - 10/2014
2	Panitumumab (Vectibix)FDA Link 09/2012 - 01/2012
1	human ERBB2 proteinIBA 06/2023
1	NivolumabIBA 01/2022
1	IpilimumabIBA 01/2022
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020
1	trofosfamideIBA 01/2020
1	Lomustine (CCNU)FDA Link 01/2020
1	Aryl Hydrocarbon Receptor Nuclear TranslocatorIBA 07/2019
1	Insulin-Like PeptidesIBA 10/2016
1	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 07/2014
1	PlatinumIBA 07/2014
1	Peptide LibraryIBA 06/2014
1	N 30IBA 06/2014
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 12/2012
1	Cetuximab (Erbitux)FDA Link 07/2012
1	PanobinostatIBA 07/2012
1	Tumor Viral Antigens (Large T Antigen)IBA 07/2012
1	ChromatinIBA 07/2012
1	Histone Deacetylases (Histone Deacetylase)IBA 07/2012
1	Histones (Histone)IBA 07/2012
1	Epirubicin (Ellence)FDA LinkGeneric 07/2012
1	AnthracyclinesIBA 07/2012
1	Histone Deacetylase InhibitorsIBA 07/2012
1	Transcription Factor AP-2IBA 01/2012
1	Factor X (Stuart Factor)IBA 07/2011
1	Cysteine Proteases (Cysteine Protease)IBA 07/2011
1	AsparagineIBA 07/2011
1	AcidsIBA 07/2011
1	cancer procoagulantIBA 07/2011
1	Dasatinib (BMS 354825)FDA Link 08/2010
1	bosutinibIBA 08/2010
1	Sunitinib (Sutent)FDA Link 08/2010
1	nilotinib FDA Link 08/2010
1	Tyrosine Kinase InhibitorsIBA 08/2010
1	Sorafenib (BAY 43-9006)FDA Link 08/2010
1	EndopeptidasesIBA 02/2010
1	CarbamatesIBA 01/2009
1	Tyrosine (L-Tyrosine)FDA Link 01/2009
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2009
1	Phosphotransferases (Kinase)IBA 01/2009
1	V 70 (V70)IBA 03/2008
1	Gemcitabine FDA Link 01/2004
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2004

Therapy/Procedure

8	Drug Therapy (Chemotherapy) 10/2014 - 01/2012
5	Therapeutics 01/2022 - 12/2012
5	Chemoradiotherapy 12/2019 - 01/2010
4	Radiotherapy 01/2020 - 01/2007
3	Combined Modality Therapy 01/2022 - 07/2012
2	Neoadjuvant Therapy 12/2019 - 08/2016
2	Combination Drug Therapy (Combination Chemotherapy) 07/2012 - 12/2010
2	Adjuvant Chemotherapy 01/2010 - 01/2007
1	Induction Chemotherapy 12/2010
1	Adjuvant Chemoradiotherapy 01/2007